In previous research, the effects of commercial vehicle proportions (CVP) on overall crash propensity have been found to be significant, but the results have been varied in terms of the effect direction. In addition, the mediating or moderating effects of roadway attributes on the CVP-vs-safety relationships, have not been investigated. In addressing this gap in the literature, this study integrates databases on crashes, traffic, and inventory for Hong Kong road segments spanning 2014–2017. The classes of commercial vehicles considered are public buses, taxi, and light-, medium- and heavy-goods vehicles. Random-parameter Tobit models were estimated using the crash rates. The results suggest that the CVP of each class show credible effects on the crash rates, for the various crash severity levels. The results also suggest that the interaction between CVP and roadway attributes is credible enough to mediate the …